Keywords
Maternal age;
Ovarian reserve;
Infertility;
Reproductive Techniques Assisted.
Abstract
Introduction: The postponement of pregnancy, combined with reproductive aging, has increased female infertility rates. Consequently, there has been a significant rise in the demand for Assisted Reproductive Techniques after 34 years of age. In addition, cryotransfer can be performed using either autologous or donor oocytes. Objective: This study aimed to analyze the success rates of embryo cryotransfers utilizing both autologous eggs and donor eggs and to correlate these rates with maternal age. Methodology: This was a quantitative cross-sectional retrospective study. A total of 380 cryotransfer in vitro fertilization cycles performed at a human reproduction center between January and December 2022 were selected. Data collected from electronic medical records included maternal age, cryotransfer type, blastocyst morphology, ovarian hyperstimulation syndrome status, preimplantation aneuploidy genetic test results, pregnancy type, and pregnancy outcome. Subsequently, the data were analyzed using Pearson's correlation coefficient, with 5% significance assessed using Student's t- test. The means and variances of patients' ages in the positive and negative groups were compared using the t-test (5%) and F- test (5%), respectively. Results: No intergroup differences were noted in patient age. Moreover, age did not interfere with assisted reproduction success. A statistically significant difference was found between age and the occurrence of chromosomal alterations in the evaluated oocytes but not between age and the occurrence of multiple genetic alterations. Conclusion: Among the observed cryotransfer cycles, the number of egg cell donation transfers increased as maternal age increased, and the couples’ fertility status was preserved after the protocols were performed regardless of maternal age, thereby demonstrating the importance and effectiveness of these methods in infertility treatment.
KEY WORDS: Fertilization in Vitro; Maternal age; Ovarian reserve; Infertility; Reproductivet.