Keywords
Cardiac arrest
Cardiovascular system
Abstract
Introduction: Cardiopulmonary arrest (CPA) is one of the most critical medical emergencies, characterized by the sudden interruption of cardiac and respiratory functions, requiring immediate intervention. Despite advances in cardiopulmonary resuscitation (CPR) techniques, mortality rates remain high. The interaction among the cardiac, renal, and circulatory systems significantly influences clinical outcomes, making it essential to understand these relationships to improve post-CPA patient management. Objective: To evaluate biomarkers and factors related to cardiopulmonary arrest. Methods: This was a cross-sectional study including patients of both sexes who experienced CPA of unspecified etiology and underwent CPR maneuvers, regardless of outcome, while hospitalized in an emergency medical service. Results: During the analyzed period, 133 patients who experienced CPA were identified, mostly admitted to intensive care units. Correlations were found between cardiac and renal comorbidities, demonstrating cardiorenal interaction. The main cardiac arrest rhythms were asystole and pulseless electrical activity, both predominantly resulting in death. Laboratory tests that showed correlations with the main outcome included urea, C-reactive protein, and basophils—all elevated. Conclusion: Unfavorable outcomes were predominant among male patients of advanced age, with associated cardiac and renal comorbidities, and with a higher prevalence of non-shockable rhythms associated with altered laboratory markers. Although the analyzed biomarkers showed modest correlations with outcomes such as death, their potential utility in identifying higher-risk patients should be further explored in future studies.