RELATIONSHIP BETWEEN COMMON INTESTINAL BACTERIA AND PARKINSON'S DISEASE

Abstract

Introduction: The discovery of a link between the composition of the intestinal microbiota has led to significant advances in the understanding of conditions such as Parkinson's disease. Objective: To analyze the correlation between intestinal bacteria and Parkinson's disease. Methods: This is an integrative literature review, as it provides a synthesis of the results obtained through published research. To guide the research, the following guiding question was adopted: "What is the relationship between intestinal bacteria and Parkinson's disease?" from the Medical Literature Analysis and Retrievel System Online database via PubMed and Google Scholar through the following Health Sciences Descriptors (DeCS): “Parkinson’s Disease”, “Gastrointestinal Microbiome” and “Inflammation” combined together by the Boolean operator AND with their respective counterparts in Mesh Terms. Results and Discussion: The relationship between common intestinal bacteria and Parkinson's disease has been the subject of growing interest in the scientific community. The discovery that the composition of the intestinal microbiota may play an important role in the development and progression of neurodegenerative disease Final Thoughts: The presence of certain intestinal bacteria, such as the Enterobacteriaceae family, has been associated with an increased risk of developing Parkinson's disease. These bacteria can produce toxic substances capable of triggering an inflammatory response in the brain and contributing to the death of dopaminergic neurons.