Keywords
Abstract
Objective: The objective of the study was to evaluate the epidemiological, genotypic and viral load (CV) profile of the hepatitis C virus (HCV). Methods: Cross-sectional analytical observational study, with data from January 2018 to December 2021. The study analyzed data referring to genotyping, CV and the HCV CV Request Form, obtained at the State Laboratory of Public Health in the state of Goiás . Results: Most cases of HCV are concentrated in the health macro-regions of the Center Southeast (42.90%) and Center West (34.15%) of the State, with a higher frequency of genotype 1 (subtypes 1a, 1b and 1d) , followed by G3 and the presence of G2, G4 and G5. G1 has been decreasing in frequency over the years, while G3 has increased. In general, 49.33% of the cases have a high CV (> 1,000,000 IU/mL). With regard to sex, 31.75% of males had CV in the same range, and females with 17.58%. The VC was considerably high, with women of childbearing age standing out, with a significantly lower VC than males. Subtype 1d and genotype 5 were identified in the Southeast and Midwest health macro-regions, respectively, uncommon in the Central region of Brazil. Conclusion: The data presented demonstrate that HCV may be expanding, with the appearance of new genotypes, subtypes and also demonstrates a change in genotypic distribution in the state of Goiás in recent years.